A comparison of the allantoin and inulin clearances for the measurement of filtration rate in the diseased human kidney.
نویسندگان
چکیده
منابع مشابه
Validity of the endogenous creatinine clearance as a measure of glomerular filtration rate in the diseased human kidney.
Twenty-five years ago Rehberg proposed the exogenous creatinine clearance for the measurement of glomerular filtration rate (1). In the dog and rabbit, this clearance provides a simple and accurate method of determining the filtration rate, coinciding with the inulin and ferrocyanide clearances (2, 3). Subsequently, Shannon (4) and Miller and Winkler (5) found in man that the exogenous creatini...
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Objective: Measurement of glomerular filtration rate (GFR) is the best determinant in assessment of kidney function for diagnostic and therapeutic purposes. As extremely accurate methods of GFR measurement (i.e. Inulin clearance) are expensive and Time-consuming and due to limitations of the 24 hour urine collection method, some formula have been developed for the GFR measurement. Here we have ...
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We compared creatinine clearances determined by enzymatic (Kodak Ektachem 700 single-slide, Boehringer Mannheim creatinine PAP) and nonenzymatic (Jaffé, HPLC) methods with glomerular filtration rate measured by inulin clearance in patients with varying degrees of renal function. The Kodak enzymatic assay gave values for creatinine 2 to 3 mg/L higher than the other methods. This resulted in sign...
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1. The reliability of [3H]inulin as a reference substance for the measurement of glomerular filtration rate (GFR) in river lampreys was investigated. 2. Simultaneously measured renal clearances of [3H]inulin and [14C]-polyethylene glycol (PEG) were not significantly different. 3. Recoveries of [3H]inulin in the urine following its injection into the proximal tubule and urinary duct averaged 83....
متن کاملDiodrast and Inulin Clearances in Nephrotic Children with Supernormal Urea Clearances.
Elevation of the urea clearance above the calculated normal value has been frequently observed in our clinic in children with the nephrotic syndrome. Previous studies of this phenomenon have shown it to be related to the intake of protein, but not induced by the oral administration of urea (1). Glomerular filtration, measured by inulin clearance, has been found by Emerson, Futcher, and Farr (2)...
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عنوان ژورنال:
- The Journal of clinical investigation
دوره 31 3 شماره
صفحات -
تاریخ انتشار 1952